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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFAP1L2
All Species:
18.18
Human Site:
S48
Identified Species:
44.44
UniProt:
Q8N4X5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4X5
NP_001001936.1
818
91300
S48
L
R
L
Y
T
K
S
S
S
S
D
E
E
Y
I
Chimpanzee
Pan troglodytes
XP_001150419
817
91217
S48
L
R
L
Y
T
K
S
S
S
S
D
E
E
Y
I
Rhesus Macaque
Macaca mulatta
XP_001092605
814
91012
S48
L
R
L
Y
T
K
S
S
S
S
D
E
E
Y
I
Dog
Lupus familis
XP_544028
1006
111817
S228
L
R
L
Y
T
K
S
S
S
S
D
E
E
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5DTU0
825
92156
S48
L
R
L
Y
T
K
S
S
S
S
D
E
E
Y
I
Rat
Rattus norvegicus
Q8VH46
731
80733
E26
Y
L
T
S
T
V
R
E
K
K
A
V
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513664
759
85321
E48
Q
L
P
I
P
K
I
E
S
P
E
G
Y
Y
E
Chicken
Gallus gallus
Q90738
729
81141
V24
H
E
Y
L
T
S
T
V
R
E
K
K
A
V
I
Frog
Xenopus laevis
Q6PF55
811
90890
N48
L
Q
L
F
I
K
S
N
S
S
C
D
E
E
Y
Zebra Danio
Brachydanio rerio
Q4V8Y7
746
84147
L41
K
K
M
A
V
K
N
L
L
R
Q
L
Q
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.9
69.9
N.A.
82.6
34.1
N.A.
67.3
33.7
57.4
35
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.7
73.4
N.A.
89.4
49.6
N.A.
76.6
51.7
72.9
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
20
13.3
46.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
26.6
26.6
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
50
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
20
0
10
10
50
60
10
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
60
% I
% Lys:
10
10
0
0
0
80
0
0
10
10
10
10
0
0
0
% K
% Leu:
60
20
60
10
0
0
0
10
10
0
0
10
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
10
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
50
0
0
0
0
10
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
10
60
50
70
60
0
0
0
0
10
% S
% Thr:
0
0
10
0
70
0
10
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
10
0
10
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
50
0
0
0
0
0
0
0
0
10
60
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _